NDAPERIARTICULARSOLUTION, EXTENDED RELEASEPriority Review
Approved
May 2021
Lifecycle
Peak
Competitive Pressure
0/100
Data completeness
3/8 — Basic
Priority Review
ZYNRELEF KIT (bupivacaine and meloxicam) by Heron Therapeutics is cyclooxygenase inhibitors [moa]. First approved in 2021.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZYNRELEF KIT is a fixed-dose combination of bupivacaine (local anesthetic) and meloxicam (NSAID) delivered as an extended-release solution for periarticular injection. It provides localized pain relief and anti-inflammatory effects at the surgical site, reducing opioid requirements post-operatively. The product targets patients undergoing orthopedic procedures requiring regional anesthesia and post-operative analgesia.
Peak10.0 years to LOE
Product is in peak commercial phase with surgical/orthopedic market penetration; commercial team likely focused on field adoption and procedure-center relationships.
Mechanism of Action
Cyclooxygenase Inhibitors
Pharmacologic Class:
Nonsteroidal Anti-inflammatory Drug
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on ZYNRELEF offers a unique opportunity in surgical pain management with a novel mechanism and minimal competitive pressure. The peak lifecycle phase and 10-year patent runway provide stable, long-term career visibility in a specialized surgical/orthopedic market.
Peri
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.