NDAINJECTIONINJECTABLE
Approved
Oct 1993
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
ZOSYN (piperacillin sodium; tazobactam sodium) by Pfizer is [ see microbiology ()] . Approved for older) for the treatment of appendicitis (complicated by rupture, abscess), peritonitis caused by beta-lactamase producing isolates of escherichia coli and 12 more indications. First approved in 1993.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZOSYN is a fixed-dose combination of piperacillin sodium (a broad-spectrum penicillin) and tazobactam sodium (a beta-lactamase inhibitor) administered by injection. It treats serious infections including complicated appendicitis, peritonitis, nosocomial pneumonia, and skin structure infections caused by beta-lactamase-producing organisms. The tazobactam component protects piperacillin from enzymatic degradation, restoring activity against resistant bacteria.
$0.260MPart D
LOE ApproachingDeclining
Product is approaching loss of exclusivity with modest Part D spending; brand team will shift focus to transition planning and generic support strategies.
Mechanism of Action
[ see Microbiology ()] .
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.