ZOFRAN
LOE ApproachingNDAORALSOLUTION
Approved
Jan 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
2/8 — Basic
Drug data last refreshed 11h ago · AI intelligence enriched 5d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZOFRAN (ondansetron) is an oral solution small molecule antiemetic that works as a 5-HT3 receptor antagonist to prevent nausea and vomiting. It is primarily indicated for chemotherapy-induced nausea and vomiting (CINV), post-operative nausea and vomiting (PONV), and radiation-induced nausea. The drug has become a standard-of-care agent across multiple therapeutic contexts since its 1997 approval.
LOE Approaching
As LOE approaches, the brand team is likely contracting; career growth opportunities center on generic transition planning, cost management, and line extension strategies rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (6)
Casopitant (Oral) And ZOFRAN To Prevent Postoperative Nausea And Vomiting In Women
Started Mar 2006
482 enrolled
Nausea and Vomiting, Postoperative
Casopitant And ZOFRAN To Prevent Post Operative Nausea And Vomiting In Women
Started Mar 2006
515 enrolled
Nausea and Vomiting, PostoperativePostoperative Nausea and Vomiting
Food Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg
Started Jul 2005
28 enrolled
Healthy
Fasting Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg
Started Jul 2005
28 enrolled
Healthy
Fasting Study of Ondansetron Tablets 24 mg and Zofran® Tablets 24 mg
Started Jul 2003
28 enrolled
Healthy
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.