NDATOPICALGEL
Approved
Nov 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
ZIANA (clindamycin phosphate and tretinoin) by Bausch + Lomb. Approved for retinoid [epc]. First approved in 2006.
Drug data last refreshed 17h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZIANA is a fixed-dose topical gel combining clindamycin phosphate (antibiotic) and tretinoin (retinoid) for acne treatment. The combination works synergistically—clindamycin provides antibacterial activity while tretinoin normalizes follicular keratinization and reduces microcomedo formation. This dual mechanism addresses both bacterial and comedonal acne in a single formulation.
$0.01BPart D
LOE ApproachingDeclining
Minimal brand investment signals; team likely focused on defensive strategy and generic preparation rather than growth expansion.
Mechanism of Action
Pharmacologic Class:
Retinoid
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on ZIANA offers limited career growth in a declining product with minimal linked job openings; roles focus on defensive strategy, generic preparation, and operational efficiency rather than innovation or expansion. Career advancement requires pivoting to higher-growth pipeline assets or transitioning into generic/biosimilar strategy functions.
Brand Manager (mature/defensive)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.