NDATOPICALGEL
Approved
Nov 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
ZIANA (clindamycin phosphate and tretinoin) by Bausch + Lomb. Approved for retinoid [epc]. First approved in 2006.
Drug data last refreshed 1h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZIANA is a fixed-dose topical gel combining clindamycin phosphate (an antibiotic) and tretinoin (a retinoid) for the treatment of acne vulgaris. The combination works synergistically by reducing bacterial colonization while simultaneously promoting cell turnover and decreasing comedone formation. This dual-mechanism approach targets both inflammatory and non-inflammatory acne lesions.
$0.01BPart D
LOE ApproachingDeclining
As a mature product approaching loss of exclusivity with minimal Part D engagement, the ZIANA brand team is likely in defensive/maintenance mode with limited growth investment and potential headcount reductions.
Mechanism of Action
Pharmacologic Class:
Retinoid
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on ZIANA offers limited growth and stability as a mature, near-LOE topical acne brand. Roles are primarily commercial and focused on defending market share against generic and branded competitors rather than driving innovation or expansion.
Brand ManagerField Sales Representative
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.