ZEPATIER

PeakSM

elbasvir and grazoprevir

NDAORALTABLETPriority Review
Approved
Jan 2016
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
6

Mechanism of Action

Breast Cancer Resistance Protein Inhibitors

Pharmacologic Class:

Hepatitis C Virus NS5A Inhibitor

Clinical Trials (5)

NCT03365635Phase 4Completed

Administration of Zepatier (Grazoprevir Plus Elbasvir) in Chronic Hemodialysis (HD) Patients With Hepatitis C

Started Sep 2019
6 enrolled
Hepatitis CHemodialysisNosocomial Infection
NCT04048850N/ACompleted

Zepatier in Patients with Substance Use

Started Sep 2019
25 enrolled
Hepatitis CHivCoinfection, HIV+1 more
NCT03026023Phase 4Withdrawn

Preemptive Zepatier Treatment in Donor HCV Positive to Recipient HCV Negative Cardiac Transplant

Started Aug 2018
0
Cardiac Transplant DisorderHepatitis C
NCT02895958Phase 4Terminated

The Dublin Zepatier Study

Started Mar 2018
3 enrolled
Hepatitis C
NCT03127358N/ACompleted

Smartphone Based aDOT Treatment With Fixed-Dose Elbasvir and Grazoprevir in PWIDs

Started Nov 2017
11 enrolled
Hepatitis CMedication Adherence

Loss of Exclusivity

LOE Date
May 4, 2031
62 months away
Patent Expiry
May 4, 2031

Patent Records (2)

Patent #ExpiryTypeUse Code
7973040
Jul 24, 2029
SubstanceProduct
U-1813
8871759
May 4, 2031
SubstanceProduct
U-1813