NDAINJECTIONINJECTABLE
Approved
May 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug Shortage Active
ZANOSAR is currently in shortage. Reason: Available. This may impact manufacturing, supply chain, and quality hiring at the manufacturer.
Drug data last refreshed 7h ago · AI intelligence enriched 9h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZANOSAR (streptozocin) is an injectable nitrosourea alkylating agent approved in 1982 for treating metastatic islet cell carcinoma of the pancreas and carcinoid tumors. It works by alkylating DNA and is particularly toxic to pancreatic beta cells, making it effective against neuroendocrine malignancies. This is a legacy chemotherapy with narrow but well-defined indications.
LOE Approaching
This is a mature, niche specialty oncology product with limited commercial infrastructure and declining team investment as loss of exclusivity approaches.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors
Started Aug 2007
1 enrolled
Pancreatic Cancer
Career Relevance
Working on ZANOSAR offers minimal career growth in traditional brand management, with no linked job openings and a shrinking team footprint. Opportunities exist primarily in niche specialty roles (MSL, specialty sales) or in supply chain/manufacturing roles managing a legacy product with documented supply constraints.
Brand Manager (Oncology)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.