NDAINJECTIONINJECTABLE
Approved
May 1982
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug Shortage Active
ZANOSAR is currently in shortage. Reason: Available. This may impact manufacturing, supply chain, and quality hiring at the manufacturer.
Drug data last refreshed 14m ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ZANOSAR (streptozocin) is an injectable chemotherapy agent approved in 1982 for treating neuroendocrine tumors, particularly pancreatic islet cell carcinomas. It is a nitrosourea-type alkylating agent that works by direct DNA damage and is administered intravenously. The drug remains a standard-of-care option for metastatic neuroendocrine tumors despite its age.
LOE Approaching
As a 40+ year-old product approaching loss of exclusivity, the brand team is likely focused on lifecycle management and defending market share against generics rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Avastin, Fluorouracil, Doxorubicin and Streptozocin in Locally Advanced and Metastatic Pancreatic Endocrine Tumors
Started Aug 2007
1 enrolled
Pancreatic Cancer
Career Relevance
Working on ZANOSAR offers limited career growth opportunities given the LOE-approaching lifecycle and minimal linked job openings (0 reported). Roles available are primarily defensive, focused on margin protection, generic defense, and compliance rather than innovative launches or market expansion.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.