NDATOPICALJELLY
Approved
Mar 1953
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
5/8 — Partial
XYLOCAINE (lidocaine hydrochloride) by AstraZeneca is 12. Approved for pain. First approved in 1953.
Drug data last refreshed 23h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
XYLOCAINE (lidocaine hydrochloride) is a local anesthetic that stabilizes neuronal membranes by inhibiting ionic fluxes required for impulse initiation and conduction. It is indicated for pain management and has been used off-label in prostate cancer contexts. The topical jelly formulation delivers rapid local anesthetic action with minimal systemic absorption.
$5KPart D
LOE ApproachingDeclining
Mature, low-volume product with minimal team expansion; career roles focused on cost management and regulatory maintenance rather than growth initiatives.
Mechanism of Action
12.1 Mechanism of Action Lidocaine hydrochloride stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. 12.2 Pharmacodynamics Excessive blood levels may cause changes in cardiac output, total…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.