NDAINJECTIONINJECTABLE
Approved
Nov 1948
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug data last refreshed 3h ago · AI intelligence enriched 9h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
XYLOCAINE (lidocaine hydrochloride with epinephrine bitartrate) is a classic local anesthetic combination approved since 1948, used for infiltration, nerve block, and topical anesthesia across surgical and procedural settings. Lidocaine blocks sodium channels to prevent nerve impulse transmission, while epinephrine causes vasoconstriction to prolong anesthetic duration and reduce bleeding. It is indicated for local and regional anesthesia in minor surgical procedures, dental work, and emergency medicine.
LOE Approaching
As an off-patent, mature injectable with moderate competitive pressure (30%), the brand team is likely focused on defensive positioning and cost-efficiency rather than expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
A Study to Characterize the Phenotype in Patients With Morton's Neuroma and to Explore the Effect of Local Administration of Xylocaine (Lidocaine)
Started Feb 2011
27 enrolled
Morton's Neuroma
Career Relevance
Working on XYLOCAINE offers stable, defensive brand stewardship in a mature injectable market where success is measured by margin protection, formulary retention, and operational efficiency rather than growth or innovation. Roles emphasize field execution, customer relationships, and cost management—valuable experience for careers in established products or generic/specialty pharma.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.