NDATOPICALCREAM
Approved
Jul 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
XERESE (acyclovir and hydrocortisone) by Bausch + Lomb is dna polymerase inhibitors [moa]. Approved for herpes simplex virus nucleoside analog dna polymerase inhibitor [epc]. First approved in 2009.
Drug data last refreshed 16h ago · AI intelligence enriched 18h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
XERESE is a fixed-dose topical cream combining acyclovir (a nucleoside analog DNA polymerase inhibitor) and hydrocortisone for the treatment of herpes simplex virus infections. It works by inhibiting viral DNA replication while providing anti-inflammatory benefit through the corticosteroid component. The combination targets both viral replication and associated inflammation in HSV lesions.
$0.483MPart D
LOE ApproachingModest Medicare utilization signals a mature product approaching loss of exclusivity, suggesting team focus on retention and life-cycle management rather than growth initiatives.
Mechanism of Action
DNA Polymerase Inhibitors
Pharmacologic Class:
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
XERESE offers limited career growth due to near-term LOE status and minimal linked job openings, making it better suited for professionals seeking transition, exit strategy planning, or dermatology specialization experience. Working on this product provides exposure to life-cycle management and late-stage commercial strategy within a declining market segment.
Brand Manager
Worked on XERESE at Bausch + Lomb? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.