NDATOPICALCREAM
Approved
Jul 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
XERESE (acyclovir and hydrocortisone) by Bausch + Lomb is dna polymerase inhibitors [moa]. Approved for herpes simplex virus nucleoside analog dna polymerase inhibitor [epc]. First approved in 2009.
Drug data last refreshed 18h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
XERESE is a fixed-dose topical cream combining acyclovir (a nucleoside analog DNA polymerase inhibitor) and hydrocortisone for the treatment of herpes simplex virus infections. The acyclovir component inhibits viral DNA replication, while hydrocortisone reduces inflammation and associated symptoms. This combination targets the localized treatment of HSV lesions on the face and lips.
$0.483MPart D
LOE ApproachingDeclining commercial activity with minimal Part D uptake signals a mature, low-volume product with limited team expansion opportunity.
Mechanism of Action
DNA Polymerase Inhibitors
Pharmacologic Class:
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on XERESE offers limited career growth opportunity; the product is in decline with minimal job openings and low commercial momentum. Professionals joining this team should expect focus on cost management, market maintenance, and transition planning rather than expansion.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.