NDATOPICALCREAM
Approved
Jul 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
XERESE (acyclovir and hydrocortisone) by Bausch + Lomb is dna polymerase inhibitors [moa]. Approved for herpes simplex virus nucleoside analog dna polymerase inhibitor [epc]. First approved in 2009.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
XERESE is a fixed-dose topical cream combining acyclovir (a nucleoside analog DNA polymerase inhibitor) and hydrocortisone for treatment of herpes simplex virus infections. It treats recurrent herpes labialis (cold sores) by inhibiting viral DNA replication while reducing inflammation. The dual mechanism addresses both viral replication and associated inflammation at the infection site.
$0.483MPart D
LOE ApproachingLimited Part D utilization and approaching loss of exclusivity signal a declining commercial footprint with potential team rightsizing or redeployment.
Mechanism of Action
DNA Polymerase Inhibitors
Pharmacologic Class:
Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
XERESE generates minimal linked career opportunities due to low market utilization, approaching LOE status, and limited clinical development. Working on this product offers experience in mature-stage brand management and lifecycle defense but limited growth trajectory.
Company
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.