XBRYK

GrowthmAb

denosumab

BLASUBCUTANEOUSINJECTABLE
Approved
Feb 2025
Lifecycle
Growth
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

RANK Ligand Blocking Activity

Pharmacologic Class:

RANK Ligand Inhibitor

Clinical Trials (5)

NCT05884372Phase 4Completed

Efficacy and Safety of Combination Denosumab With Eldecalcitol for Postmenopausal Women With Osteoporosis.(ESCORT)

Started Aug 2023
100 enrolled
Osteoporosis in Postmenopausal Women
NCT04586660Phase 4Active Not Recruiting

Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone

Started Aug 2023
36 enrolled
Giant Cell Tumor of Bone
NCT04711109Phase 3Active Not Recruiting

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation

Started Feb 2023
300 enrolled
BRCA1 MutationBreast CancerBreast Diseases+3 more
NCT05405725Phase 3Completed

A Phase 3 Study to Compare Biosimilar Denosumab With Prolia®

Started Jul 2022
504 enrolled
Postmenopausal Osteoporosis
NCT05245669Phase 1Completed

Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers

Started Jan 2022
207 enrolled
Healthy Male Subjects