WAYRILZ

Launch

rilzabrutinib

NDAORALTABLET
Approved
Aug 2025
Lifecycle
Launch
Competitive Pressure
0/100
Clinical Trials
19

Mechanism of Action

Bruton's Tyrosine Kinase Inhibitors

Pharmacologic Class:

Kinase Inhibitor

Clinical Trials (5)

NCT07007962Phase 3Recruiting

Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment

Started Oct 2025
60 enrolled
Immune Thrombocytopenia
NCT07216079Phase 3Active Not Recruiting

Rilzabrutinib for the Adult Participants With Chronic ITP Who Have Completed Phase 3 Study in Japan

Started Oct 2025
4 enrolled
Immune Thrombocytopenia
NCT07190196Phase 3Recruiting

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Started Sep 2025
124 enrolled
Immunoglobulin G4 Related Disease
NCT06984627Phase 2Recruiting

A Study to Investigate the Efficacy and Safety of Rilzabrutinib in Adult Participants With Graves' Disease

Started Sep 2025
30 enrolled
Graves' Disease
NCT07086976Phase 3Recruiting

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

Started Aug 2025
90 enrolled
Autoimmune Haemolytic Anaemia

Loss of Exclusivity

LOE Date
Feb 20, 2041
182 months away
Patent Expiry
Feb 20, 2041
Exclusivity Expiry
Aug 29, 2030

Patent Records (5)

Patent #ExpiryTypeUse Code
9580427
Mar 1, 2033
SubstanceProduct
8940744
Sep 6, 2033
SubstanceProduct
U-4270
9266895
Sep 6, 2033
SubstanceProduct
U-4268
9994576
Sep 6, 2033
SubstanceProduct
U-4269
12178818
Oct 13, 2040
U-4267