NDASUBCUTANEOUSSOLUTION
Approved
Dec 2023
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
9
Data completeness
4/8 — Partial
WAINUA (AUTOINJECTOR) (eplontersen) by AstraZeneca. Approved for transthyretin-directed rna interaction [epc]. First approved in 2023.
Drug data last refreshed 20h ago
Mechanism of Action
Pharmacologic Class:
Transthyretin-directed RNA Interaction
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (9)
The Eplontersen Pregnancy and Lactation Outcomes Study
Started Nov 2025
10 enrolled
Transthyretin Amyloidosis
A Study to Assess the PK, PD, Safety and Tolerability of Eplontersen in Healthy Chinese Volunteers
Started Aug 2024
12 enrolled
Transthyretin-mediated Amyloidosis
EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy
Started Dec 2023
64 enrolled
Transthyretin Amyloid Cardiomyopathy
An Extension Study to Assess Long-Term Safety of Eplontersen in Adults With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
Started Nov 2022
1,400 enrolled
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
A Study to Assess the Long-Term Safety and Efficacy of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Patients With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
Started Jan 2022
151 enrolled
Hereditary Transthyretin-Mediated Amyloid Polyneuropathy
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.