NDAORALTABLET
Approved
Sep 1967
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
VIVACTIL (protriptyline hydrochloride) by Teva is clinical pharmacology protriptyline hydrochloride is an antidepressant agent. Approved for symptoms of mental depression in patients. First approved in 1967.
Drug data last refreshed 7h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VIVACTIL (protriptyline hydrochloride) is a tricyclic antidepressant approved in 1967 for treating symptoms of mental depression. It works through an unknown mechanism that does not involve monoamine oxidase inhibition or primary CNS stimulation, with a notably faster onset than comparable agents like imipramine. The drug is administered orally as a tablet and lacks significant sedative properties.
LOE Approaching
This legacy product faces moderate competitive pressure (30/100) with declining market relevance, suggesting smaller brand teams focused on maintenance and cost-efficiency rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Protriptyline hydrochloride is an antidepressant agent. The mechanism of its antidepressant action in man is not known. It is not a monoamine oxidase inhibitor, and it does not act primarily by stimulation of the central nervous system. Protriptyline has been found in some…
Indications (1)
Career Relevance
Working on VIVACTIL offers limited career acceleration; this is a maintenance product managed by smaller, specialized teams focused on cost containment and regulatory compliance rather than market expansion. Professionals should seek roles emphasizing operational efficiency and risk management rather than commercial innovation.
Worked on VIVACTIL at Teva? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.