NDAORALCAPSULE
Approved
Nov 1968
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
VISTARIL (hydroxyzine pamoate) by Pfizer is clinical pharmacology hydroxyzine pamoate is unrelated chemically to the phenothiazines, reserpine, meprobamate, or the benzodiazepines. Approved for anxiety. First approved in 1968.
Drug data last refreshed 19h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VISTARIL (hydroxyzine pamoate) is an oral anxiolytic capsule approved in 1968 for anxiety treatment. It works by suppressing activity in key subcortical CNS regions and demonstrates muscle relaxant, bronchodilator, antihistaminic, analgesic, and antiemetic properties. Clinical effects typically appear within 15-30 minutes of oral administration.
LOE Approaching
As an approaching LOE product with 30% competitive pressure, brand teams face declining revenue trajectory and likely reduced headcount allocation in coming years.
Mechanism of Action
CLINICAL PHARMACOLOGY Hydroxyzine pamoate is unrelated chemically to the phenothiazines, reserpine, meprobamate, or the benzodiazepines. Hydroxyzine pamoate is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the…
Indications (1)
Clinical Trials (1)
Does Preventive Analgesia Improve the Outcome of Demerol-Vistaril Procedural Sedations in Pediatric Dentistry
Started Oct 2013
88 enrolled
Pain
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.