NDAORALSUSPENSION
Approved
Jun 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
VISTARIL (hydroxyzine pamoate) by Pfizer is clinical pharmacology hydroxyzine pamoate is unrelated chemically to the phenothiazines, reserpine, meprobamate, or the benzodiazepines. Approved for anxiety. First approved in 1959.
Drug data last refreshed 41m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VISTARIL (hydroxyzine pamoate) is an oral anxiolytic suspension approved in 1959 for anxiety treatment. It works by suppressing activity in key subcortical CNS regions and demonstrates skeletal muscle relaxant, antihistaminic, analgesic, and antiemetic properties. Clinical effects typically appear within 15–30 minutes of oral administration.
$0.017BPart D
LOE ApproachingDeclining
Mature product approaching loss of exclusivity with limited claims volume; brand team focus likely on retention and generic transition planning rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Hydroxyzine pamoate is unrelated chemically to the phenothiazines, reserpine, meprobamate, or the benzodiazepines. Hydroxyzine pamoate is not a cortical depressant, but its action may be due to a suppression of activity in certain key regions of the subcortical area of the…
Indications (1)
Clinical Trials (1)
Does Preventive Analgesia Improve the Outcome of Demerol-Vistaril Procedural Sedations in Pediatric Dentistry
Started Oct 2013
88 enrolled
Pain
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.