NDAINJECTIONINJECTABLE
Approved
Aug 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
5/8 — Partial
VISIPAQUE 320 (iodixanol) by GE HealthCare is x-ray contrast activity [moa]. Approved for radiographic contrast agent [epc]. First approved in 1997.
Drug data last refreshed 5h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VISIPAQUE 320 (iodixanol) is an osmotically balanced, nonionic radiographic contrast agent administered via injection for diagnostic X-ray imaging procedures. It provides enhanced visualization of vascular and organ structures during angiography, coronary intervention, and other radiographic examinations. Iodixanol works by absorbing X-rays, creating contrast between tissues and enabling detailed radiographic imaging.
LOE Approaching
As a mature product approaching loss of exclusivity with moderate competitive pressure (30), brand teams face margin compression and shifting focus toward retained revenue and cost management.
Mechanism of Action
X-Ray Contrast Activity
Pharmacologic Class:
Radiographic Contrast Agent
Indications (1)
Clinical Trials (6)
Comparing Patient Comfort and Safety Between Iodixanol and Iopamidol in Patients Undergoing Peripheral Arteriography
Started Oct 2011
255 enrolled
Drug Safety
Iodixanol Versus Iopamidol in Patients Undergoing Contrast-Enhanced Computed Tomographic Imaging of Abdomen/Pelvis
Started May 2011
304 enrolled
Patient Comfort and Safety
Renal Safety of Iopamidol Versus Iodixanol During Coronary Angiography in Diabetic Patients
Started Mar 2009
23 enrolled
Chronic Renal ImpairmentDiabetes Mellitus
Safety and Effectiveness of Visipaque 320mg-I/ml for Use in Contrast-Enhanced CT Angiography of Arteries of the Heart
Started Jun 2006
66 enrolled
Coronary Artery Disease
Safety and Effectiveness of Visipaque 320mg-I/ml for Use in Contrast-Enhanced CT Angiography of Arteries of the Heart
Started May 2006
89 enrolled
Coronary Artery Disease
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.