NDAORALFOR SUSPENSION
Approved
Dec 1967
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
VIBRAMYCIN (doxycycline) by Pfizer is 12. First approved in 1967.
Drug data last refreshed 16h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VIBRAMYCIN (doxycycline) is an oral tetracycline antibiotic approved in 1967, primarily used to treat bacterial infections and inflammatory conditions including rosacea. The mechanism of action in rosacea is unknown, but doxycycline exhibits broad-spectrum antimicrobial activity through inhibition of bacterial protein synthesis. It is available as capsules and for-suspension formulations with a half-life of approximately 21–23 hours.
$0.005BPart D
LOE ApproachingProduct approaching loss of exclusivity with minimal Part D utilization, indicating contracted team focus on cost management and generic transition planning rather than growth initiatives.
Mechanism of Action
12.1 Mechanism of Action The mechanism of action of doxycycline in the treatment of inflammatory lesions of rosacea is unknown. 12.3 Pharmacokinetics Doxycycline capsules are not bioequivalent to other doxycycline products. The pharmacokinetics of doxycycline following oral administration of…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.