NDAORALTABLET
Approved
Oct 1986
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
VASERETIC (enalapril maleate and hydrochlorothiazide) by Bausch + Lomb. Approved for thiazide diuretic [epc]. First approved in 1986.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VASERETIC is a fixed-dose oral combination of enalapril maleate (an ACE inhibitor) and hydrochlorothiazide (a thiazide diuretic) approved in 1986 for hypertension management. It works by inhibiting angiotensin-converting enzyme to reduce vasoconstriction and aldosterone secretion, while the diuretic component enhances sodium and water excretion. The combination is equally effective across racial populations, addressing a clinical gap where monotherapy efficacy varies by ethnicity.
$0.081BPart D
LOE ApproachingDeclining
As LOE approaches, commercial teams are likely consolidating efforts; limited brand investment and shrinking market presence suggest lean staffing models.
Mechanism of Action
Pharmacologic Class:
Thiazide Diuretic
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on VASERETIC offers limited career growth opportunity given its LOE status and minimal linked job openings (0 current). Positions are likely focused on managed decline, generic transition management, and cost-optimization rather than brand growth or innovation. This is a consolidation/legacy product environment suitable for operationally-focused professionals rather than high-visibility commercial roles.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.