NDAINJECTIONINJECTABLE
Approved
Feb 2007
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Data completeness
2/8 — Basic
Drug data last refreshed 3h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VAPRISOL (conivaptan hydrochloride) is an intravenous vaptан—a vasopressin V1a/V2 receptor antagonist—approved for hyponatremia in hospitalized patients. It works by blocking vasopressin-mediated water reabsorption in the kidney, promoting aquaresis and sodium concentration restoration. The drug targets euvolemic and hypervolemic hyponatremia across multiple etiologies.
LOE Approaching
As LOE approaches, VAPRISOL teams are likely in harvest/transition mode with reduced headcount and focus shifting toward managed care and hospital formulary defense.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (3)
A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic Hyponatremia
Started Feb 2012
4 enrolled
Hyponatremia
Diuretic and Renal Effects of Vaprisol When Administered Along With Furosemide and Nesiritide Continuous Infusion
Started Oct 2008
0Heart Failure
Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients
Started Aug 2008
6 enrolled
Hyponatremia
Career Relevance
Working on VAPRISOL in a LOE-approaching phase offers limited growth upside but valuable experience in harvest-phase product management, formulary defense, and hospital-based channel strategy. Roles emphasize relationship management and margin protection over expansion.
Worked on VAPRISOL at Cumberland Pharmaceuticals? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.