NDANASALSPRAY
Approved
Jan 2020
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
8
Data completeness
6/8 — Strong
VALTOCO (diazepam) by Neurelis is mechanism of action although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with γ-aminobutyric acid (gaba) receptors of the a-type (gaba a ). Approved for epilepsy, alcohol withdrawal syndrome, seizures. First approved in 2020.
Drug data last refreshed 20h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
VALTOCO is a nasal spray formulation of diazepam, a benzodiazepine approved by the FDA in January 2020 for the treatment of epilepsy. The drug works by enhancing the action of GABA, the brain's primary inhibitory neurotransmitter, which reduces neuronal excitability and prevents seizure generation and spread. This novel nasal delivery system offers an alternative to traditional oral or injectable diazepam formulations, providing rapid onset of action for acute seizure management.
$0.0BPart D
6.4 years to LOEMechanism of Action
Mechanism of Action Although the precise mechanism by which diazepam exerts its antiseizure effects is unknown, animal and in vitro studies suggest that diazepam acts to suppress seizures through an interaction with γ-aminobutyric acid (GABA) receptors of the A-type (GABA A ). GABA, the major…
Pharmacologic Class:
Benzodiazepine
Indications (3)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.