NDAORALTABLET
Approved
Mar 2024
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
26
Data completeness
5/8 — Partial
VAFSEO (vadadustat) by Akebia Therapeutics is hypoxia-inducible factor prolyl hydroxylase inhibitors [moa]. Approved for anemia of chronic kidney disease. First approved in 2024.
Drug data last refreshed 21h ago
Mechanism of Action
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors
Pharmacologic Class:
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitor
Indications (1)
Clinical Trials (26)
Vadadustat for the Treatment of Nonintubated Acute Respiratory Distress Syndrome Due to Pathogen-Associated Lung Injury
Started Oct 2025
1,100 enrolled
Nonintubated Acute Respiratory Distress Syndrome (ARDS)Pathogen-associated Lung Injury
To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis
Started Jul 2025
353 enrolled
Anemia of Chronic Kidney Disease
Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease Naive to Erythropoiesis-Stimulating Agents
Started Jan 2025
0Anemia of Chronic Kidney Disease
Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease
Started Jan 2025
0Anemia of Chronic Kidney Disease
Vafseo Outcomes In-Center Experience
Started Nov 2024
2,200 enrolled
Anemia of Chronic Kidney Disease
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.