VAFSEO

GrowthSM

vadadustat

NDAORALTABLET
Approved
Mar 2024
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors

Pharmacologic Class:

Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitor

Clinical Trials (5)

NCT07086755Phase 2/3Recruiting

Vadadustat for the Treatment of Nonintubated Acute Respiratory Distress Syndrome Due to Pathogen-Associated Lung Injury

Started Oct 2025
NCT06901505Phase 3Active Not Recruiting

To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis

Started Jul 2025
NCT05082584Phase 3Withdrawn

Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease Naive to Erythropoiesis-Stimulating Agents

Started Jan 2025
NCT05082571Phase 3Withdrawn

Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease

Started Jan 2025
NCT06520826Phase 3Recruiting

Vafseo Outcomes In-Center Experience

Started Nov 2024

Loss of Exclusivity

LOE Date
Mar 31, 2036
122 months away
Patent Expiry
Mar 31, 2036
Exclusivity Expiry
Mar 27, 2029

Patent Records (5)

Patent #ExpiryTypeUse Code
RE47437
Jun 26, 2027
SubstanceProduct
8940773
Jun 26, 2027
U-3876
8598210
Jun 26, 2027
SubstanceProduct
8343952
Aug 14, 2027
SubstanceProduct
7811595
Mar 13, 2028
SubstanceProduct