NDAINJECTIONINJECTABLE
Approved
Feb 1999
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
3/8 — Basic
UVADEX (methoxsalen) by Teva is photoabsorption [moa]. First approved in 1999.
Drug data last refreshed 4h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
UVADEX (methoxsalen) is an injectable photoabsorption agent that functions as a photoactivated radical generator for extracorporeal photochemotherapy. It is indicated for treatment of cutaneous T-cell lymphoma (mycosis fungoides) and other photosensitive dermatologic conditions. The drug works by absorbing UV-A radiation to generate reactive oxygen species that induce apoptosis in circulating lymphocytes.
LOE Approaching
Product approaching loss of exclusivity with low competitive pressure (30%) suggests a consolidating commercial team focused on retained market share rather than expansion.
Mechanism of Action
Photoabsorption
Pharmacologic Class:
Photoactivated Radical Generator
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease
Started May 2020
24 enrolled
Acute-graft-versus-host Disease
Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD)
Started Nov 2011
60 enrolled
Chronic Graft Versus Host Disease
Career Relevance
UVADEX offers limited entry-level or high-growth career opportunities due to mature product status and approaching LOE. Positions available are primarily defensive, focused on market share retention, reimbursement, and physician relationship maintenance in a specialized dermatology/hematology segment.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.