NDAORALTABLET
Approved
Oct 1948
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
URECHOLINE (bethanechol chloride) by Teva is clinical pharmacology bethanechol chloride acts principally by producing the effects of stimulation of the parasympathetic nervous system. Approved for acute postoperative, postpartum nonobstructive (functional) urinary retention, for neurogenic atony of the urinary bladder with retention. First approved in 1948.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Urecholine (bethanechol chloride) is a parasympathomimetic agent approved in 1948 for treating nonobstructive urinary retention and neurogenic bladder atony. It works by stimulating acetylcholine receptors on bladder and GI smooth muscle, increasing detrusor tone and promoting micturition without crossing the blood-brain barrier. The drug is available as an oral tablet with effects typically appearing within 60-90 minutes and lasting up to 6 hours at higher doses.
LOE Approaching
As an aging product approaching loss of exclusivity with minimal current market activity, career opportunities on the brand team are likely limited and focused on maintenance rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Bethanechol chloride acts principally by producing the effects of stimulation of the parasympathetic nervous system. It increases the tone of the detrusor urinae muscle, usually producing a contraction sufficiently strong to initiate micturition and empty the bladder. It…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.