UNIVASC
LOE ApproachingNDAORALTABLET
Approved
Apr 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
UNIVASC by UCB Pharma is mechanism of action moexipril hydrochloride is a prodrug for moexiprilat, which inhibits ace in humans and animals. First approved in 1995.
Drug data last refreshed 11h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
UNIVASC (moexipril hydrochloride) is an oral ACE inhibitor prodrug approved in 1995 for hypertension management. It works by inhibiting angiotensin-converting enzyme (ACE), reducing angiotensin II formation and decreasing vasoconstriction, plasma renin activity, and aldosterone secretion. The active metabolite moexiprilat is approximately 1000 times more potent than the parent compound at ACE and kininase II inhibition.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30% intensity), signaling potential consolidation or transition of commercial team focus.
Mechanism of Action
Mechanism of Action Moexipril hydrochloride is a prodrug for moexiprilat, which inhibits ACE in humans and animals. The mechanism through which moexiprilat lowers blood pressure is believed to be primarily inhibition of ACE activity. ACE is a peptidyl dipeptidase that catalyzes the conversion of…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.