BLAINJECTIONINJECTABLEPriority Review
Approved
Dec 2018
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
37
Data completeness
5/8 — Partial
Priority Review
ULTOMIRIS (ravulizumab) by AstraZeneca is complement inhibitors [moa]. First approved in 2018.
Drug data last refreshed 22h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
ULTOMIRIS (ravulizumab) is a monoclonal antibody complement inhibitor administered via injection for rare complement-mediated diseases. It works by blocking the C5 component of the complement cascade, preventing downstream inflammatory cascade activation. The drug targets patients with life-threatening or severely debilitating complement-driven conditions.
$160MPart D
PeakPeak-stage lifecycle suggests mature team with focus on market defense, payer negotiations, and protecting share against emerging competitors in the complement inhibitor space.
Mechanism of Action
Complement Inhibitors
Pharmacologic Class:
Complement Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (37)
Efficacy, Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity Study of Ravulizumab in Chinese Adults With Neuromyelitis Optica Spectrum Disorder (NMOSD)
Started Aug 2026
19 enrolled
NMOSDNeuromyelitis Optica Spectrum Disorder
Efficacy and Safety of Ravulizumab in Chinese Adults Participants With Generalized Myasthenia Gravis (gMG)
Started Jul 2026
20 enrolled
Generalized Myasthenia GravisgMG
Ravulizumab Outcomes in Polish Patients With aHUS
Started Apr 2026
80 enrolled
Atypical Hemolytic Uremic Syndrome
A Study to Investigate OCS Tapering in Adult Participants With Generalized Myasthenia Gravis Treated With Ravulizumab
Started Mar 2026
75 enrolled
Generalized Myasthenia GravisgMG
Proteomic Changes in Patients With Myasthenia Gravis and Ravulizumab
Started Jan 2026
24 enrolled
Myasthenia Gravis Generalised
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.