TWIRLA

LOE Approaching

levonorgestrel/ethinyl estradiol

NDATRANSDERMALSYSTEM
Approved
Feb 2020
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Clinical Trials
4

Mechanism of Action

Estrogen Receptor Agonists

Pharmacologic Class:

Estrogen

Clinical Trials (4)

NCT06380205Phase 1Completed

A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult Females

Started May 2024
24 enrolled
Healthy Participants
NCT06071442Phase 1Completed

Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine

Started Jan 2024
60 enrolled
Healthy Participants
NCT03547024Phase 1Completed

A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

Started Jun 2018
14 enrolled
Healthy
NCT00447863Phase 1Withdrawn

Study Evaluating the Bioequivalence of Levonorgestrel/Ethinyl Estradiol Combinations in Cycling Women

Started Aug 2007
0
Contraception

Loss of Exclusivity

LOE Date
Aug 26, 2028
30 months away
Patent Expiry
Aug 26, 2028

Patent Records (3)

Patent #ExpiryTypeUse Code
8747888
Jul 10, 2028
Product
9050348
Jul 10, 2028
Product
8246978
Aug 26, 2028
Product