TUSSIONEX PENNKINETIC
LOE ApproachingNDAORALSUSPENSION, EXTENDED RELEASE
Approved
Dec 1987
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
TUSSIONEX PENNKINETIC by UCB Pharma is clinical pharmacology hydrocodone is a semisynthetic narcotic antitussive and analgesic with multiple actions qualitatively similar to those of codeine. First approved in 1987.
Drug data last refreshed 2h ago · AI intelligence enriched 2mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TUSSIONEX PENNKINETIC is an extended-release oral suspension combining hydrocodone (semisynthetic opioid antitussive) and chlorpheniramine (antihistamine) for cough suppression. Hydrocodone acts directly on the cough center while chlorpheniramine prevents histamine-induced respiratory mucosa edema. The Pennkinetic delivery system provides controlled, prolonged release over an extended dosing interval.
LOE Approaching
As LOE approaches, the brand team is likely in defensive mode with focus on retention programs and cost optimization rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Hydrocodone is a semisynthetic narcotic antitussive and analgesic with multiple actions qualitatively similar to those of codeine. The precise mechanism of action of hydrocodone and other opiates is not known; however, hydrocodone is believed to act directly on the cough…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.