TRYVIO

Growth

aprocitentan

NDAORALTABLET
Approved
Mar 2024
Lifecycle
Growth
Competitive Pressure
0/100
Clinical Trials
3

Mechanism of Action

Endothelin Receptor Antagonists

Pharmacologic Class:

Endothelin Receptor Antagonist

Clinical Trials (3)

NCT04162366Phase 3Withdrawn

A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease.

Started Jan 2020
0
HypertensionRenal Insufficiency, Chronic
NCT03586570Phase 1Completed

A Study to Evaluate How Aprocitentan is Safe and How it is Absorbed and Broken Down in the Body of Japanese and Caucasian Subjects

Started Jul 2018
20 enrolled
Healthy Subjects
NCT03541174Phase 3Completed

A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its Safety

Started Jun 2018
730 enrolled
Resistant Hypertension

Loss of Exclusivity

LOE Date
Jul 26, 2038
150 months away
Patent Expiry
Jul 26, 2038
Exclusivity Expiry
Mar 22, 2029

Patent Records (5)

Patent #ExpiryTypeUse Code
8324232
Sep 21, 2029
SubstanceProduct
U-3878
11174247
Nov 6, 2037
U-3879
10919881
Feb 26, 2038
SubstanceProduct
12297189
Feb 26, 2038
Product
11787782
Mar 2, 2038
U-3877