NDAORALTABLETPriority Review
Approved
Nov 2023
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
29
Data completeness
4/8 — Partial
Priority Review
Drug data last refreshed 17h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TRUQAP (capivasertib) is an oral small-molecule AKT inhibitor developed by AstraZeneca and approved in November 2023. The drug is indicated for hormone receptor-positive (HR+) breast cancer in combination with endocrine therapy. It works by inhibiting AKT signaling, a key pathway in cancer cell survival and proliferation.
$0.002BPart D
Growth6.4 years to LOEEarly-stage product with minimal Part D claims signals nascent market penetration; expect growing commercial team investment as awareness and adoption ramp.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (29)
Adding Capivasertib to Standard Treatment in HR Positive, HER2 Negative Metastatic Breast Cancer Based on ctDNA Testing
Started Oct 2026
1,084 enrolled
HR Positive/HER-2 Negative Breast Cancer
HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Started Oct 2026
42 enrolled
Acute Lymphoblastic LeukemiaLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) RecurrentLymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory+2 more
Rash & Diarrhea Prophylaxis With Capivasertib
Started Aug 2026
108 enrolled
Metastatic HR+/HER2- Breast Cancer
A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Dextromethorphan (CYP2D6 Substrate) in Healthy Participants
Started Mar 2026
42 enrolled
Healthy Participants
A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment
Started Jan 2026
20 enrolled
Moderate Hepatic Impairment
Worked on TRUQAP at AstraZeneca? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.