TROPHAMINE
LOE Approachingisoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, valine, cysteine hydrochloride, histidine, tyrosine, n-acetyl-tyrosine, alanine, arginine, proline, serine, glycine, aspartic acid, glutamic acid, and taurine
NDAINJECTIONINJECTABLE
Approved
Jul 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
TROPHAMINE (isoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, valine, cysteine hydrochloride, histidine, tyrosine, n-acetyl-tyrosine, alanine, arginine, proline, serine, glycine, aspartic acid, glutamic acid, and taurine) by B. Braun is clinical pharmacology trophamine® provides a mixture of essential and nonessential amino acids as well as taurine and a soluble form of tyrosine, n-acetyl-l-tyrosine (nat). Approved for nitrogen, weight loss, treat negative nitrogen balance in infants and 5 more indications. First approved in 1984.
Drug data last refreshed 6h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TrophAmine is a sterile parenteral amino acid injection containing 20 essential and nonessential amino acids plus taurine and N-acetyl-L-tyrosine, specifically formulated for pediatric total parenteral nutrition (TPN). It is indicated to provide nitrogen source and treat negative nitrogen balance in infants and young pediatric patients when oral, gastrostomy, or jejunostomy feeding is not feasible. When combined with cysteine hydrochloride, dextrose, electrolytes, vitamins, and minerals, it normalizes plasma amino acid concentrations to match breast-fed infants and supports improved nutritional status.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30); expect organizational consolidation and focus on operational efficiency rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY TrophAmine® provides a mixture of essential and nonessential amino acids as well as taurine and a soluble form of tyrosine, N-Acetyl-L-Tyrosine (NAT). This amino acid composition has been specifically formulated to provide a well tolerated nitrogen source for nutritional…
Pharmacologic Class:
Amino Acid
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.