TROPHAMINE
LOE Approachingisoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, valine, cysteine hydrochloride, histidine, tyrosine, n-acetyl-tyrosine, alanine, arginine, proline, serine, glycine, aspartic acid, glutamic acid, and taurine
NDAINJECTIONINJECTABLE
Approved
Jul 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
TROPHAMINE (isoleucine, leucine, lysine acetate, methionine, phenylalanine, threonine, tryptophan, valine, cysteine hydrochloride, histidine, tyrosine, n-acetyl-tyrosine, alanine, arginine, proline, serine, glycine, aspartic acid, glutamic acid, and taurine) by B. Braun is clinical pharmacology trophamine® provides a mixture of essential and nonessential amino acids as well as taurine and a soluble form of tyrosine, n-acetyl-l-tyrosine (nat). Approved for nitrogen, weight loss, treat negative nitrogen balance in infants and 5 more indications. First approved in 1984.
Drug data last refreshed 22m ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TROPHAMINE is a parenteral amino acid injection containing 20 essential and non-essential amino acids, taurine, and N-Acetyl-L-Tyrosine formulated specifically for pediatric total parenteral nutrition (TPN). It treats negative nitrogen balance and weight loss in infants and young children when oral, gastrostomy, or jejunostomy feeding is not feasible. When combined with cysteine hydrochloride, dextrose, electrolytes, vitamins, and minerals, it normalizes plasma amino acid concentrations to match breast-fed infant profiles and supports improved nutritional status.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%) signals potential team contraction and shift toward brand defense and cost management strategies.
Mechanism of Action
CLINICAL PHARMACOLOGY TrophAmine® provides a mixture of essential and nonessential amino acids as well as taurine and a soluble form of tyrosine, N-Acetyl-L-Tyrosine (NAT). This amino acid composition has been specifically formulated to provide a well tolerated nitrogen source for nutritional…
Pharmacologic Class:
Amino Acid
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.