NDAVAGINALCREAM
Approved
Apr 2000
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
8
Data completeness
3/8 — Basic
TRIVAGIZOLE 3 (clotrimazole) by PharmaIN is clinical pharmacology clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and malassezia furfur . First approved in 2000.
Drug data last refreshed 4h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TRIVAGIZOLE 3 is a clotrimazole vaginal cream, a broad-spectrum azole antifungal approved in 2000 for topical treatment of dermal and vaginal fungal infections. It works by disrupting fungal cell membranes, causing leakage of intracellular phosphorus compounds and nucleic acid breakdown. The drug exhibits fungistatic and fungicidal activity against dermatophytes, yeasts, and Candida species with minimal systemic absorption.
LOE Approaching
Product is in late-stage lifecycle with approaching loss of exclusivity; brand team focus will shift toward generic transition strategy and potential line extension opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY Clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and Malassezia furfur . The primary action of clotrimzole is against dividing and growing organisms. In vitro ,…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.