NDAORALTABLET
Approved
Sep 2013
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
21
Data completeness
4/8 — Partial
Drug data last refreshed 13h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Trintellix (vortioxetine) is an oral small-molecule antidepressant approved in 2013 that works through multimodal serotonergic activity. It is indicated for major depressive disorder in adults and offers a differentiated mechanism combining serotonin reuptake inhibition with receptor modulation. The drug is designed to improve mood, cognition, and functional outcomes in depression.
$390MPart D
Peak6.0 years to LOEProduct is at peak commercialization with $390M in annual Part D spending and 602k+ claims, indicating stable market presence and established teams.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (21)
Compare the Efficacy and Safety of KH607 Tablets Versus Vortioxetine Hydrobromide Tablets in Adult Patients With Major Depressive Disorder
Started Jul 2026
326 enrolled
Major Depressive Disorder (MDD)
A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive Disorder
Started Oct 2025
180 enrolled
Major Depressive Disorder
Vortioxetine for the Treatment of Mood and Cognitive Symptoms in Frontotemporal Dementia
Started Mar 2025
50 enrolled
Fronto-temporal DementiaFronto-temporal Lobar DementiaFrontotemporal Degeneration+3 more
A Database Survey of Comparison The Risk of Haemorrhage Between Vortioxetine Tablet Treatment and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment in Participants With Depression
Started Jun 2024
147,777 enrolled
Major Depressive Disorder
Vortioxetine for Post-COVID-19 Condition
Started Sep 2021
149 enrolled
Post-COVID-19 ConditionPost-COVID-19 SyndromeCognitive Impairment
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.