Mechanism of Action
understood, but is thought to be related to its enhancement of serotonergic activity in the CNS through inhibition of the reuptake of serotonin (5-HT). It also has several other activities including 5-HT3 receptor antagonism and 5-HT1A receptor agonism. The contribution of these activities to…
Indications (1)
Clinical Trials (5)
A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive Disorder
A Database Survey of Comparison The Risk of Haemorrhage Between Vortioxetine Tablet Treatment and Selective Serotonin Reuptake Inhibitor (SSRI) Treatment in Participants With Depression
Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes
Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine
Loss of Exclusivity
Patent Records (5)
| Patent # | Expiry | Type | Use Code |
|---|---|---|---|
| 7144884 | Jun 17, 2026 | SubstanceProduct | U-1439 |
| 7144884*PED | Dec 17, 2026 | — | |
| 11458134 | Jun 15, 2027 | Product | U-3463 |
| 8969355 | Jun 15, 2027 | U-1668 | |
| 9125908 | Jun 15, 2027 | U-2309 |