NDAOPHTHALMICSOLUTION/DROPSPriority Review
Approved
Mar 2001
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
3/8 — Basic
Priority Review
TRAVATAN (travoprost) by Alcon is acid, a prostaglandin analog is a selective fp prostanoid receptor agonist, which is believed to reduce iop by increasing uveoscleral outflow. First approved in 2001.
Drug data last refreshed 4h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TRAVATAN (travoprost) is a prostaglandin analog ophthalmic solution that reduces intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. It works as a selective FP prostanoid receptor agonist, believed to lower IOP by increasing uveoscleral outflow, though the exact mechanism remains incompletely understood. Administered as daily eye drops, it has been a standard-of-care therapy since approval in 2001.
LOE Approaching
As LOE approaches, the brand team is likely focused on lifecycle extension, generic mitigation, and maximizing remaining patent-protected revenue rather than growth initiatives.
Mechanism of Action
acid, a prostaglandin analog is a selective FP prostanoid receptor agonist, which is believed to reduce IOP by increasing uveoscleral outflow. The exact mechanism of action is unknown at this time.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Started Feb 2026
510 enrolled
Glaucoma
Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcg
Started Dec 2025
30 enrolled
Open Angle Glaucoma (OAG)Ocular Hypertension (OH)
Phase 2/Phase 3 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant
Started Jun 2025
610 enrolled
Glaucoma
Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular Hypertension
Started Nov 2023
250 enrolled
Open Angle GlaucomaOcular Hypertension
Travoprost Intraocular Implant + iStent Infinite
Started Sep 2023
150 enrolled
Glaucoma, Open-Angle
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.