NDAINJECTIONINJECTABLEPriority Review
Approved
Sep 2007
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 5h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TOTECT (dexrazoxane hydrochloride) is an injectable small-molecule cardioprotective agent approved to reduce the incidence and severity of cardiomyopathy associated with doxorubicin administration in patients with metastatic breast cancer. It works as a topoisomerase II inhibitor that binds iron and reduces free radical formation in cardiac tissue.
LOE Approaching
LOE-approaching status suggests reduced commercial investment and team contraction; product likely in maintenance mode with limited growth trajectory.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Efficacy and Safety of Cytotect®CP, Hyperimmune Anti-CMV IVIg as CMV Prophylaxis in Patients Developing Acute Grade II-IV GVHD After Allogeneic Hematopoietic Cell Transplantation.
Started Sep 2022
2 enrolled
Cytomegalovirus Infections
Career Relevance
TOTECT currently shows zero linked job openings, reflecting its niche market position and LOE-approaching status. Career opportunities are limited primarily to maintenance-focused commercial roles with limited growth potential.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.