NDAINJECTIONINJECTABLEPriority Review
Approved
Sep 2007
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 13h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TOTECT (dexrazoxane hydrochloride) is an intravenous injection used to mitigate cardiotoxicity associated with anthracycline chemotherapy extravasation. It acts as a cytoprotective agent by chelating free iron and reducing oxidative stress in cardiac and surrounding tissues. This adjunctive therapy addresses a serious complication of cancer treatment rather than treating cancer itself.
LOE Approaching
As LOE approaches, the brand team is likely consolidating and shifting focus toward lifecycle extension strategies or transition planning, suggesting limited growth opportunities in core commercial roles.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Efficacy and Safety of Cytotect®CP, Hyperimmune Anti-CMV IVIg as CMV Prophylaxis in Patients Developing Acute Grade II-IV GVHD After Allogeneic Hematopoietic Cell Transplantation.
Started Sep 2022
2 enrolled
Cytomegalovirus Infections
Career Relevance
TOTECT presents limited career growth due to its niche indication, approaching LOE, and zero linked job postings, indicating a mature, small team with few openings. Professionals joining this product should expect a consolidation phase rather than expansion, with career progression tied to defensive market strategies and potential transition planning.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.