TOPROL-XL

LOE Approaching

metoprolol succinate

NDAORALTABLET, EXTENDED RELEASE
Approved
Jan 1992
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
11

Clinical Trials (5)

NCT05767346Phase 3Completed

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

Started Jun 2023
175 enrolled
Obstructive Hypertrophic Cardiomyopathy (oHCM)
NCT01508325Phase 4Completed

Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients

Started Dec 2011
Hypertension
NCT00273052Phase 3Completed

COREG MR Versus TOPROL-XL On The Lipid Profile Of Normolipidemic Or Mildly Dyslipidemic Patients With Hypertension

Started Jan 2006
514 enrolled
Hypertension
NCT00861016Phase 4Completed

Efficacy and Safety of Metoprolol Succinate Prolonged-Release Tablet in Patients With Mild to Moderate Hypertension

Started Oct 2005
310 enrolled
Hypertension
NCT00123903Phase 3Terminated

COREG MR Versus TOPROL-XL On Reduction Of Microalbuminuria In Patients With Hypertension And Microalbuminuria

Started Jul 2005
1,220 enrolled
Heart Failure, Congestive and Microalbuminuria