TOLVAPTAN (tolvaptan) by Otsuka is vasopressin v2 receptor antagonists [moa]. Approved for clinically significant hypervolemic, euvolemic hyponatremia [serum sodium <125 meq/l, less marked hyponatremia and 4 more indications. First approved in 2020.
Drug data last refreshed 19h ago
Vasopressin V2 Receptor Antagonists
Vasopressin V2 Receptor Antagonist
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A Study to See Iftolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old withAutosomal Recessive Polycystic Kidney Disease (ARPKD)
Probenecid (PB) to Treat Hereditary Nephrogenic Diabetes Insipidus (NDI), ADPKD Treated With Tolvaptan, and Severely Polyuric Patients With Previous Lithium Administration
A Study to See if Tolvaptan Can Delay Dialysis in Infants and Children Who at Enrollment Are 28 Days to Less Than 12 Weeks Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Tolvaptan add-on Therapy to Overcome Loop Diuretic Resistance in Acute Heart Failure With Renal Dysfunction
Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease