NDAORALTABLET
Approved
Jul 1974
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
2/8 — Basic
Drug data last refreshed 2h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Tolbutamide is a first-generation sulfonylurea oral antidiabetic agent approved in 1974 for the treatment of type 2 diabetes mellitus. It works by stimulating insulin secretion from pancreatic beta cells to lower blood glucose levels. This is a small molecule therapeutic indicated for patients with non-insulin-dependent diabetes.
LOE Approaching
As a legacy product approaching loss of exclusivity with minimal ongoing commercial investment, career opportunities on this brand are limited and typically involve maintenance-mode operations.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Study to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of Tolbutamide
Started Nov 2021
12 enrolled
Healthy Volunteers
Career Relevance
Tolbutamide currently has zero linked job openings and represents a legacy asset with minimal career momentum. Working on this product offers limited exposure to innovation, market growth, or career advancement opportunities.
Brand Manager (Legacy)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.