TOBREX
LOE ApproachingNDAOPHTHALMICSOLUTION/DROPS
Approved
Dec 1980
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
TOBREX by Novartis is clinical pharmacology in vitro data: in vitro studies have demonstrated tobramycin is active against susceptible strains of the following microorganisms: staphylococci , including s. Approved for the treatment of external infections of the eye, its adnexa caused by susceptible bacteria. First approved in 1980.
Drug data last refreshed 8h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TOBREX is a tobramycin ophthalmic solution approved in 1980 for bacterial eye infections. It is a small-molecule aminoglycoside antibiotic administered as eye drops. The drug works by inhibiting bacterial protein synthesis to treat ocular infections.
$0.057BPart D
LOE ApproachingLimited commercial opportunity as product approaches loss of exclusivity with minimal linked job openings and declining lifecycle stage.
Mechanism of Action
CLINICAL PHARMACOLOGY In Vitro Data: In vitro studies have demonstrated tobramycin is active against susceptible strains of the following microorganisms: Staphylococci , including S. aureus and S. epidermidis (coagulase-positive and coagulase-negative), including penicillin-resistant strains.…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.