BLAVIAL
Approved
Jun 2000
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
2/8 — Basic
Drug data last refreshed 1h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TNKASE (tenecteplase) is a fibrinolytic agent approved in 2000 for acute myocardial infarction (AMI). It is a genetically engineered variant of tissue plasminogen activator (tPA) that converts plasminogen to plasmin to dissolve blood clots. The drug is administered intravenously as a rapid bolus injection.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30/100); team is likely in defensive/optimization mode rather than growth expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Tenecteplase (TNK) in the Treatment of Intracerebral Hemorrhage (ICH)
Started Sep 2026
5 enrolled
Intracerebral HemorrhageIntracranial HemorrhagesHemorrhagic Strokes
A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well
Started Feb 2026
1,325 enrolled
Acute Ischemic Stroke
Intra-Arterial Tenecteplase to Improve the Microvascular Hemodynamics After Mechanical Thrombectomy
Started Feb 2026
20 enrolled
Acute Ischemic Stroke From Large Vessel Occlusion
Intra-arterial Tenecteplase for Acute Medium Vessel Occlusion Stroke
Started Jan 2026
488 enrolled
Ischemic StrokeMedium Vessel OcclusionTenecteplase+1 more
Tenecteplase Before Interhospital Transfer for EVT in Acute Anterior Circulation LVO at 4.5-24 Hours
Started Jan 2026
572 enrolled
Acute Ischemic StrokeLarge Vessel OcclusionTransportation of Patients
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.