THORAZINE
LOE ApproachingNDAORALTABLETPriority Review
Approved
Nov 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Priority Review
Drug data last refreshed 22h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
THORAZINE (chlorpromazine) is an oral tablet small-molecule antipsychotic approved in 1957 as a pioneering first-generation agent. The exact indications are not fully specified in available data, but historically it has been used for psychotic disorders and severe behavioral disturbances. It works primarily through dopamine antagonism in the central nervous system.
LOE Approaching
As a decades-old agent approaching loss of exclusivity with moderate competitive pressure (30), the brand team is likely focused on cost management and niche positioning rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
With zero linked open positions and approaching loss of exclusivity, THORAZINE offers limited career growth; roles that do exist focus on managing the product's decline and transition to generic. Assignment to this product is typically a maintenance role, not a launchpad for advancement.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.