NDAINJECTIONSOLUTIONPriority Review
Approved
Dec 1965
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
2/8 — Basic
Priority Review
Drug data last refreshed 17h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
THAM (tromethamine) is an alkalizing agent administered by injection as a solution. It is used to correct metabolic acidosis, particularly in clinical settings such as cardiac bypass surgery and severe respiratory or metabolic acidosis. The drug works by accepting hydrogen ions and increasing blood pH.
LOE Approaching
As a legacy product approaching LOE with minimal linked job postings, the commercial team is likely small and focused on retention rather than expansion.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Methamphetamine Use Disorder Support in Heart Failure Pilot Study
Started May 2026
50 enrolled
Heart FailureMethamphetamine Use Disorder
A Single-Dose Study to Evaluate Safety and Efficacy of CS-1103 in Participants Receiving a Single Dose of Methamphetamine
Started Feb 2026
40 enrolled
Methamphetamine IntoxicationMethamphetamine DisordersMethamphetamine Abuse
Maternal Outcomes With Methamphetamine Use and Cardiac Assessment for Rural Dissemination (MOM CARD)
Started Feb 2026
35 enrolled
Methamphetamine Abuse
Testing an Accelerated TMS Protocol for Methamphetamine Use Disorder
Started Sep 2024
20 enrolled
Methamphetamine Use Disorder
Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement
Started Aug 2024
200 enrolled
Methamphetamine UseHeart Failure
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.