NDAORALTABLET
Approved
Dec 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
4/8 — Partial
TEVETEN (eprosartan mesylate) by AbbVie is mechanism of action eprosartan: angiotensin ii (formed from angiotensin i in a reaction catalyzed by angiotensin-converting enzyme [kininase ii]), a potent vasoconstrictor, is the principal pressor agent of the renin-angiotensin system. Approved for hypertension. First approved in 1997.
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TEVETEN (eprosartan mesylate) is an oral angiotensin II receptor antagonist (ARB) approved in 1997 for essential hypertension management. It selectively blocks AT1 receptors to reduce vasoconstriction and aldosterone secretion, with 1,000-fold greater affinity for AT1 versus AT2 receptors. The drug is available as a tablet in monotherapy and combination formulations (TEVETEN HCT with hydrochlorothiazide).
LOE Approaching
TEVETEN faces imminent loss of exclusivity with limited Part D spending data; expect team consolidation and transition focus toward managed care and generic support rather than expansion initiatives.
Mechanism of Action
Mechanism of Action Eprosartan: Angiotensin II (formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme [kininase II]), a potent vasoconstrictor, is the principal pressor agent of the renin-angiotensin system. Angiotensin II also stimulates aldosterone synthesis and…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.