TERRAMYCIN W/ POLYMYXIN B SULFATE
LOE Approachingoxytetracycline hydrochloride; polymyxin b sulfate
NDAOPHTHALMICOINTMENT
Approved
Jul 1965
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
1/8 — Limited
Drug data last refreshed 3h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Terramycin w/ Polymyxin B Sulfate is a fixed-dose combination ophthalmic ointment containing oxytetracycline hydrochloride (a tetracycline antibiotic) and polymyxin B sulfate (a polymyxin antibiotic) for topical eye infections. This dual-antibiotic formulation provides broad-spectrum coverage against bacterial pathogens affecting the eye. The combination mechanism relies on oxytetracycline's protein synthesis inhibition and polymyxin B's disruption of bacterial cell membranes.
LOE Approaching
As an aging product approaching loss of exclusivity with moderate competitive pressure (30% competitive intensity), the commercial team is likely small and focused on defensive positioning in legacy ophthalmology segments.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on Terramycin w/ Polymyxin B offers experience in legacy product stewardship, generic competition dynamics, and niche market defense—valuable for professionals seeking expertise in post-LOE portfolio management. This role emphasizes operational efficiency, customer relationships, and regulatory compliance over growth-stage innovation and market expansion.
Product Manager (legacy portfolio management)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.