TEPEZZA

PeakmAb

teprotumumab

BLAINJECTIONINJECTABLEPriority Review
Approved
Jan 2020
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
14

Mechanism of Action

Insulin-like Growth Factor-1 Receptor Inhibitors

Pharmacologic Class:

Insulin-like Growth Factor-1 Receptor Inhibitor

Clinical Trials (5)

NCT07142642Phase 1Completed

A Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Teprotumumab (AMG 632) Administered Intravenously in Healthy Chinese Participants

Started Aug 2025
20 enrolled
Healthy Volunteers
NCT07085117N/ACompleted

Real World Study to Describe the Effectiveness and Safety of Teprotumumab Among Thyroid Eye Disease Patients

Started Jul 2025
5 enrolled
Thyroid Eye Disease
NCT06248619Phase 3Active Not Recruiting

A Trial to Investigate Teprotumumab Subcutaneous Administration Compared With Placebo in Male and Female Adult Participants With Moderate-to-severe Active Thyroid Eye Disease

Started Jul 2024
89 enrolled
Thyroid Eye Disease
NCT06674941Phase 1Completed

A Trial to Investigate Teprotumumab (High-concentration Formulation) Subcutaneous Administration in Healthy Adult Non-Japanese and Japanese Participants

Started Mar 2023
44 enrolled
Healthy Volunteers
NCT06389578Phase 1Completed

A Study of TEPEZZA® Treatment in Participants With Thyroid Eye Disease

Started Jul 2022
16 enrolled
Thyroid Eye Disease
Data Sources
  • Drug label: DailyMed / FDA
  • Clinical trials: ClinicalTrials.gov
  • Patent data: FDA Orange Book
  • Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.