NDAORALTABLET
Approved
Aug 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
TEPANIL (diethylpropion hydrochloride) by Teva is clinical pharmacology diethylpropion hydrochloride is a sympathomimetic amine with some pharmacologic activity similar to that of the prototype drugs of this class used in obesity, the amphetamines. Approved for the management of exogenous obesity, higher. First approved in 1959.
Drug data last refreshed 3d ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TEPANIL (diethylpropion hydrochloride) is a sympathomimetic amine oral tablet approved in 1959 for the management of exogenous obesity. It works by stimulating the central nervous system and elevating blood pressure to suppress appetite, with active metabolites believed to cross the blood-brain barrier. Weight loss benefit averages a fraction of a pound per week over placebo, with greatest effect in initial weeks of therapy.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30) indicates defensive positioning and likely cost-control focus over expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Diethylpropion hydrochloride is a sympathomimetic amine with some pharmacologic activity similar to that of the prototype drugs of this class used in obesity, the amphetamines. Actions include some central nervous system stimulation and elevation of blood pressure. Tolerance…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.