NDAORALTABLET
Approved
Aug 1981
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
15
Data completeness
4/8 — Partial
TENORMIN (atenolol) by Lavipharm is adrenergic beta-antagonists [moa]. First approved in 1981.
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TENORMIN (atenolol) is a selective beta-1 adrenergic blocker approved in 1981 for the treatment of hypertension, angina, and coronary artery disease. It works by reducing heart rate and contractility, thereby lowering blood pressure and myocardial oxygen demand. The drug is indicated across nine cardiovascular conditions including left ventricular hypertrophy, atherosclerotic CVD, and perioperative hypertension.
$4MPart D
LOE ApproachingDeclining
Generic erosion and LOE approaching signal a contracting brand team focused on cost management and niche positioning rather than growth initiatives.
Mechanism of Action
Adrenergic beta-Antagonists
Pharmacologic Class:
beta-Adrenergic Blocker
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (15)
A Randomized Controlled Study to Assess the Effects of Bisoprolol and Atenolol on Resting Heart Rate and Sympathetic Nervous System's Activity in Subjects With Essential Hypertension
Started Nov 2010
177 enrolled
Hypertension
Effect of Carvedilol Controlled-Release (CR) and Atenolol on Central Blood Pressure
Started Apr 2008
41 enrolled
Hypertension
Phase 1 Drug Interaction Study of Apixaban and Atenolol in Healthy Subjects
Started Jun 2007
15 enrolled
N/A - Healthy Subjects
Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients
Started Dec 2005
30 enrolled
Hypertension
Efficacy and Safety of Aliskiren and Atenolol in Adults (>18) With Mild to Moderate Hypertension
Started Nov 2005
693 enrolled
Hypertension
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.