NDATOPICALCREAM
Approved
Dec 1985
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
14
Data completeness
3/8 — Basic
TEMOVATE (clobetasol propionate) by Sandoz is clinical pharmacology: the corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. First approved in 1985.
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TEMOVATE (clobetasol propionate) is a super-potent topical corticosteroid cream approved in 1985 for treating inflammatory skin conditions including psoriasis, atopic dermatitis, and seborrheic dermatitis. It works by reducing inflammation, itching, and vasodilation through anti-inflammatory and immunosuppressive mechanisms characteristic of corticosteroids. The drug is absorbed through the skin and metabolized hepatically, with potential for transient HPA axis suppression with prolonged use.
LOE Approaching
Product is approaching loss of exclusivity with limited current commercial team investment; career growth opportunities are declining as the brand transitions toward generic competition.
Mechanism of Action
CLINICAL PHARMACOLOGY: The corticosteroids are a class of compounds comprising steroid hormones secreted by the adrenal cortex and their synthetic analogs. In pharmacologic doses, corticosteroids are used primarily for their anti-inflammatory and/or immunosuppressive effects. Topical…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.