TECENTRIQ by Roche is l1 may be expressed on tumor cells and/or tumor infiltrating immune cells and can contribute to the inhibition of the anti-tumor immune response in the tumor microenvironment. Approved for following platinum-containing chemotherapy, metastatic hepatocellular carcinoma (hcc), metastatic melanoma [see ] and 2 more indications. First approved in 2016.
Drug data last refreshed 3d ago
L1 may be expressed on tumor cells and/or tumor infiltrating immune cells and can contribute to the inhibition of the anti-tumor immune response in the tumor microenvironment. Binding of PD L1 to the PD 1 and B7.1 receptors found on T cells and antigen presenting cells suppresses cytotoxic T-cell…
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