TAGRISSO

PeakSM

osimertinib

NDAORALTABLETPriority Review
Approved
Nov 2015
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Kinase Inhibitors

Pharmacologic Class:

Kinase Inhibitor

Clinical Trials (5)

NCT07153055Phase 1/2Not Yet Recruiting

Lurbinectedin With Osimertinib in Transformed Small Cell Lung Cancer

Started May 2026
16 enrolled
Small Cell Lung Cancer ( SCLC )Transformed Small Cell Lung Cancer
NCT07295821Phase 2Not Yet Recruiting

Osimertinib Induction and Maintenance for Chemo-ineligible Stage III Unresectable EGFR+ NSCLC: Single-arm Study

Started Mar 2026
60 enrolled
Lung Cancer
NCT07323641Phase 2Not Yet Recruiting

Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer

Started Feb 2026
60 enrolled
Lung Non-Small Cell Carcinoma
NCT07279935Phase 4Not Yet Recruiting

Osimertinib Combined With Chemotherapy in Patients Who Had Distant Recurrence After Adjuvant Osimertinib for EGFRm Resectable SIB-IIIA NSCLC.

Started Jan 2026
100 enrolled
Non-small Cell Lung Cancer
NCT07058519Phase 2Recruiting

A Study of Osimertinib-based Adaptive Treatment Guided by ctDNA EGFRm+ Monitoring in NSCLC

Started Sep 2025
250 enrolled
Locally Advanced or Metastatic EGFRm Non-small Cell Lung Cancer (NSCLC)

Loss of Exclusivity

LOE Date
Nov 26, 2042
203 months away
Patent Expiry
Nov 26, 2042
Exclusivity Expiry
Dec 18, 2027

Patent Records (5)

Patent #ExpiryTypeUse Code
11524951
Jul 25, 2032
SubstanceProduct
9732058
Jul 25, 2032
SubstanceProduct
U-3823
8946235
Aug 8, 2032
SubstanceProduct
U-3823
10183020
Jan 2, 2035
Product
U-3823
12465608
Nov 26, 2042
U-3823