NDAORALTABLET
Approved
Jun 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
6
Data completeness
3/8 — Basic
TAGAMET HB (cimetidine) by Teva is histamine h2 receptor antagonists [moa]. First approved in 1995.
Drug data last refreshed 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
TAGAMET HB (cimetidine) is a histamine H2 receptor antagonist oral tablet approved in 1995 that reduces gastric acid secretion. It is indicated for peptic ulcer disease, upper gastrointestinal bleeding, and stress ulcer prophylaxis. The drug works by blocking H2 receptors on gastric parietal cells to suppress acid production.
LOE Approaching
Product is approaching loss of exclusivity with minimal data on current spending, indicating a legacy brand in decline with likely small, stable commercial teams.
Mechanism of Action
Histamine H2 Receptor Antagonists
Pharmacologic Class:
Histamine-2 Receptor Antagonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (6)
Effect of Cimetidine on the PK of Imeglimin
Started Jun 2018
16 enrolled
Healthy
Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy Subjects
Started Jan 2018
14 enrolled
Healthy Subjects
Drug-drug Interaction Study of CHF5993 With Cimetidine
Started May 2014
25 enrolled
COPD
Evaluating The Effects Of Cimetidine On The Elimination Of PD 0332334 From The Body
Started Jan 2009
12 enrolled
Generalized Anxiety Disorder
Effect of Cimetidine on the Single-Dose PK of IV- Administered MNTX
Started Jan 2007
18 enrolled
Healthy Adult Subjects
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.